RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
Sirt3
RNA ID
64384
RNA Type
mRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
30250024
Title
SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis
Year
2018
Function
SIRT3 deficiency promotes abnormal glycolysis which is responsible for the fibrogenic pathway in diabetic kidney.